![Tim Blake Nelson](http://image.tmdb.org/t/p/w92/dcfdSmVmklb1HXHbB9kySdrl9Nq.jpg)
In 19th century Baltimore, Isabel Porter, a girl stricken with grief from her parents' untimely death, voluntarily checks herself into the Rosewood Institute. Subjected to bizarre and increasingly violent pseudo-scientific experiments in personality modification, brainwashing and mind control, she must escape the clutches of the Rosewood and exact her revenge, or else be forever lost.